The Effect of Bacterial Infections on Some Hematological Parameters in Patients with Leukemia

Abstract

Objective: Our research aims to evaluate correlation between D-Dimer, Platelets (PLT), Prothrombin time (PT) and bacterial infection in patients with acute leukemia.

Method: The research took place between October 2021 and May 2022. Karbala Health Directorate / Imam Hussein Center for Oncology and Hematology. A venous blood sample of 10 mL was obtained from 104 acute leukemia patients and 50 healthy volunteers. We must follow critical blood culturing procedures, following which Hematological parameters must be determined (D-Dimer, PLT and PT).

Results: 104 new acute leukemia (AL) cases, A total of 62 patients (59.62%) were males and 42 patients (40.38%) were females, with 48 (46.15%) diagnosed with acute lymphoblastic leukemia (ALL) and 56 (53.85%) diagnosed with acute myeloid leukemia (AML), 16 with bacterial infection and 88 without bacterial infection. 50 healthy persons, 28 persons (56%) were male and 22 persons (44%) female, the results of D-Dimer(1586.492) ng/ml, PLT(132.826) µl,, PT(14.801) sec.

Conclusions: the study were presented association between of high level of D-Dimer and bacterial infections in leukemia patients, while PT and PLT level were not related with infection, but related with disease