Biochemical comparison between DMII Iraqi patients with hypertension, who take hypertensive drugs and others not take a drug

Abstract

To measure the levels of some biochemical parameters between diabetes mellitus type 2 hypertensive patients under hypertensive treatment and non-take hypertensive treatment and compare it with healthy controls. Methods: This cross-sectional study was conducted in the Al-Zahra Teaching Hospital in the city of AL-Kut, Iraq, from November 2021 to March 2022. A total of 106 patients, 46 type II DM with hypertension individuals as cases divided into two groups (23 DM cases under antihypertensive treatment and 23 cases have no treatment) and 60 healthy individuals. In both, groups, biochemical measurement of Serum electrolytes (Na+, K+, Cl, Ca, Mg, and phosphate), HbA1c was studied, and the results were compared. Results: Diabetes mellitus Individuals under antihypertensive treatment sodium and phosphate showed a significant decrease (p-value less or equal to 0.01) and increase in potassium levels (p-value less than or equal to 0.05). While diabetes mellitus no antihypertensive treatment There was a significant increase in serum sodium levels which was found to be statistically highly significant (p-value less than or equal to 0.01). Conclusion: This study concludes that there is a significant association between sodium with antihypertensive treatment in patients with type 2 diabetes mellitus. Thus, serum electrolytes have to be routinely monitored in diabetic individuals since electrolyte derangements are markedly found in diabetes hypertension patients.