Preparation and Characterization of New Formazan Compounds Derivatives from 4-Methyl-O-Phenylenediamine and Study of Their Biological Activity

Abstract

This study involves the synthesis of some formazan derivatives starting from reacting 4-Methyl-o-phenylenediamine with anthranilic acid to gate imidazole derivative(Ma), (Ma) react with chloro acetyl chloride to give compound (Mb) also (Mb) react with hydrazine hydrate to give compound (Mc) then (Mc) react with 4-Bromo benzaldehyde to product Schiff base derivative (M), then (M) react with different amine compounds to get formazan derivatives . All these compounds are characterized by, Fourier transforms infrared spectroscopy (FTIR), 1HMNR. After that , we study the biological activity for all formazan derivatives to ward two different kinds of bacteria.