HIV-Related Oral Manifestations and Their Correlation with Haart & Cd4+T-Cells and Oral Considerations-An Insight into Literature

Abstract

Human immunodeficiency virus (HIV) infection is one of the major health problems of the last decades. This disease causes a chronic infection that can lead to acquired immunodeficiency syndrome (AIDS).The aim of the review is to enlighten the HIV-related oral manifestations and their correlation with HAART & CD4+T-cells.This review also gives an insight into oral consideration in HIV-positive patients.Oral manifestations of human immunodeficiency virus include candidiasis, oral hairy leukoplakia, oral ulcers, oral warts, oral lymphoma and Kaposi's sarcoma and some other presentations.Oral candidiasis, oral hairy leukoplakia, Kaposi’s sarcoma and HSV infection are the lesions that have seen the major drop in their incidence after the HAART introduction.The increase in CD4+ T-cell count is not significantly correlated to the decrease of every type of oral lesions, but it is statistically significant only in relation to oral candidiasis.The prevalence of this disease is still high because of many risk factors, like the difficulty to access treatment, poor oral hygiene, low socioeconomic status and late diagnosis.