Synthesis and Characterization of Some Compounds Derived from 2-(1,1-dimethyl-1,3-dihydro-2H-benzo[e]indol-2-ylidene) malonaldehyde

Abstract

In this research, a series of new indole derivatives (C₁-C₄) were successfully synthesized by the condensation reaction of 2-(1,1-dimethyl-1,3-dihydro-2H-benzo[e]indol-2-ylidene) malonaldehyde with different amine compounds such as (2,4-dinitro phenyl hydrazine, thiosemicarbazide, P-Phenylendiamine). The compounds (C₅- C₆) were prepared through the reaction of compound (C₃) with anhydrous anhydride (malice anhydride, phthalic anhydride), while as compound (C₇) was synthesized by the condensation of compound(C₃) with 2-aminophenol. The purity of the compounds was confirmed by thin layer chromatography (TLC) and the structure of the synthesized compounds were deduced by using some spectroscopic techniques (FT-IR) and nuclear resonance spectroscopy Magnetic (¹H-NMR