Role of Nursing Immunocompromised Patients and COVID-19 in oral Candidiasis Infection

Abstract

Oral candidiasis is the most common fungal infection that frequently occurs in patients debilitated by other diseases or conditions. also known as "thrush," is a fungal infection of the tongue and other oral mucosal sites marked by fungal overgrowth and invasion of superficial tissues. The aims of Study are assessment Role of nursing immunocompromised patients and COVID-19 in oral candidiasis infection. Material and methods: This study included a total of one hundred and twenty-two samples were collected from COVID-19 patients with suspected of associated with oral candidiasis. All patients had laboratory confirmed COVID-19 infection with positive SARS-CoV-2 RTPCR from nasopharyngeal swabs or respiratory secretions. Patients were hospitalized at Al–Zahra Hospital during the period from 15 October 2021 to 15 April 2022.  Results: The results were appearance 58/122 (47.5%) of COVID-19 patients were infected with oral candidiasis, the result showed 58 Candida isolates out of 122 samples of (Nasal, sputum, throat swab) were collected based on culture, morphological and commercially available ID –YST card system (Vitek 2 system Bio Mèrieux, France for pathogenic yeast) were carried out in various setting phenotyping identification tests for Candida spp. The highest percentage among isolated Candida spp belonged C.albicans 27/58 (46.5%) C. parapsilosis was 13/58 (22.4%) , followed by C.tropicals 11/58 (18.9%) and the lowest percentage was for C.kruse 7/58. In this study Out of 58 patients 50 was immunocompromised patients: As 23 (46%) Diabetes, 13 (26%) Hypertension, 6 (12%) cardiovascular disease, 4(8%) lung disease, 3 (6%) Liver cirrhosis and 1 (2%) with chronic kidney disease. The results of present study showed that high percentage of infection were in third week of Hospitalization 36/58 (62%) (p˂0.05), while the low percent was in fiist week 2/58(3.4%) (p˂0.05),