Evaluation of Some adipokines Levels in Pre and Postmenopausal Osteoporosis Women

Abstract

The most frequent form of chronic metabolic bone disease is osteoporosis, which is defined by increased bone fragility. Osteoporosis can be linked to a variety of variables, including menopause and age. Because menopause and advanced age produce an imbalance between the rates of resorption and creation (resorption becomes higher than absorption), the risk of fractures increases. The participants' ages varied from 18 to 76 years old, and the research was carried out at the Dijla Hospital for Medical Rehabilitation in Tikrit. The study began in December 2021 and continued until April 2022. The overall number of subjects was 80 people, with 50 of them being pre and postmenopausal women who had osteoporosis (25 for each group), and the remaining 30 being pre and postmenopausal women who were healthy (15 for each group). According to the results of our research, premenopausal and postmenopausal women who had osteoporosis had significantly higher levels of the hormones resistin, adiponectin, and chemerin compared to the control group. The research came to the conclusion that there was an increase in adipokines, which are regarded to be diagnostic indicators for the osteoporosis condition.