Application of Microwave against Protoscoleces of Echinococcus Granulosus in Vitro and Secondary Hydatid Disease in BALB/C Mice

Abstract

The present research investigated the impact of microwave of (230-240V-50Hz 900W) on the viability of Echinococcus granulosus protoscoleces in vitro, for different exposing periods, 3, 5, 7, 10, 12, 13, 15 seconds, respectively, subsequently prevention of mice against infestation with secondary hydatid cysts, in comparison with the control animals infested with protoscoleces without exposure to microwaves, along four months, depending on many criteria including the numbers, weights and diameters of developed hydatid cysts. The results revealed an obvious infl of microwaves on Echinococcus granulosus protoscoleces viability by increase of exposure period in vitro, 90%, 80%, 77%, 70%, 50, 30 and 0%, respectively, in addition to a decrease of 97%, 92.5% of hydatid cysts numbers in the mice injected with exposed protoscoleces with 30% fertility exposed for 13 seconds, 4 months post infection, followed by 92.5% and 87.2% in the same group, two and three months post infection.