Evaluation of Some Fertility Hormones in Patients Women of Polycystic Ovary Syndrome with Recurrent Miscarriages

Abstract

Hormonal changes related with menstruation problems, such as low and high hormone concentrations, have significant consequences on the body .PCOS (polycystic ovarian syndrome) is a prevalent endocrine condition that affects women of reproductive age. The prevalence of PCOS in women of reproductive age ranges from 5% to 18%, according to a systematic review and meta-analysis. Objective:- The purpose of this study were to evaluate the levels of FSH, LH, ESTROGEN, progesterone and testosterone hormones in the serum of women who suffer from recurrent miscarriage with PCOS and to compare it with women of the control group. Subjects and method: - A case and control study includes 90 women in reproductive age (15-45), 50 of them had polycystic ovarian syndrome diagnosed, and 40 female were control group healthy. Samples were taken from October 2021 to March 2022, and FSH, LH, ESTROGEN, progesterone and testosterone levels had analyzed by CL-900i from mindray company in china. Result: - The levels of FSH was insignificantly increased (P=0.02), LH level was insignificantly increased (P=0.01), progesterone level was insignificantly increased in patients women when compared with control group, ESTROGENS level was significantly increased (P=0.01) of patients, testosterone level was equal in patients when compared with control group. Conclusion: - The levels of FSH, LH, ESTROGEN and progesterone was increase in patients women with PCOS, while testosterone level was equal in patients and control group. BMI of FSH concentration was higher in patients in normal and obese when compared with overweight, but LH levels was highest BMI level in normal, overweight and obese when compared with control group, while the levels of ESTROGENS concentration in patients were the highest in BMI normal and overweight when compared with the obese women, the levels of testosterone and progesterone concentration in patients were the highest in BMI of normal weight from control group when compared with the women of pre obesity(over weight) and obese.