Determination the Level of the D Binding Protein in the Patients with Chronic Plaque Psoriasis in the Iraq and its Relation with Disease Severity

Abstract

Psoriasis is chronic disease characterized increase the proliferation and decrease the differentiation of the keratinocyte due to the many conditions such as immune imbalance, genetic or infection or or environmental condition. 89 patients was included in the presented study additionally to the 89 control and estimated for the level of the vitamin D binding protein in the blood sample. The level of the vitamin D binding protein was higher in the patients group than the control group and there is a strong correlation of the level of the vitamin D binding protein with the disease severity. The author of the presented study opinion about these higher level of the vitamin D binding protein is attributed to the these protein considered as acute phase reactant protein and its level can increase at any acute phase of the any disease which may decrease the level of the vitamin D in the body and increasing the disease severity.