Equilibrium and Kinetic Studies of Adsorption of HCQ Drug onto Carrageenan/Carboxymethyl Cellulose-G-Poly Acrylic Acid Hydrogel

Abstract

Carrageenan/Carboxyl Methyl Cellulose-g-poly acrylic acid (CG/CMC-g-P (AA) as super adsorbent hydrogel nano-composite using a free radical polymerization process of HCQ drug. The structure and morphology of the hydrogel nano-composites were studied using FTIR and FE-SEM, different parameter that affected of the adsorption method were studied, counting effect of solution pH, effect of weight of hydrogel and effects of solution temperature. Thermodynamic factor at different temperature (15, 20, 25 and 30°C), It was found that the adsorption method spontaneous. Thermodynamic factor for the adsorption method of drug, that negative value of the enthalpy indicates that the drug adsorption method is exothermic process.