Determination TT4 and FT4 Levels and Hematological Parameters among Pregnant Women

Abstract

The current study was amid to determine the T T 4 and FT4 Levels and some hematological parameters in the pregnant women. The determination of changes in some blood components was archived on 20 pregnant women and 10 non-pregnant women using measurement of the complete blood picture RBC, HGB, HCT in the blood serum. Measuring the level of free T4 and T4 thyroxin hormones in the serum of pregnant and healthy women attend to the Al-Shams Medical Laboratory in Baqubah. The result of this study shows the mean value of RBCs parameter was low in the pregnant (4.28±0.46), whereas the control showed 5.02±0.35, and no significant different at P>0.05. The mean value of HGB was low in the Pregnant (11.35±1.24), while in the control was 14.10±1.10 with significant different at P<0.05. In addition, the mean value of HCT was low in the pregnant (34.66±9.16) compared with the control (41.78±3.22) with significant different at P≤ 0.05. The mean value of TT4 was higher in the pregnant (162.76±31.63) than the control (5.02±0.35) with significant different at P<0.05, and the mean value of FT4 in the pregnant (15.73±2.61) was lower than control (22.11±5.04). The highest sensitivity of TT4 and FT4 were 100% and 50% respectively, RBCs (15%), HGB (12%) and HCT (20%) showed the sensitivity with significant different at p<0.05. Depending on specificity of HgB, RBCs and HCT a highest specificity (90%, 70% and 60%) respectively, while, the specificity of TT4 (50%) and FT4 (40%) showed a significant different at p<0.05. The RBCs parameter was positive correlation with of HGB (r=0.472*), TT4 (r=0.281), and FT4 (r= 0.020). HCT parameter showed the positive correlation with RBCs (r= 0.438) and HGB (r=0.462*) while there is a negative correlation with FT4 (r= -0.167) and TT4 (r= - 0.095), and FT4 and TT4 showed a high significant positive correlation. In conclusion, the red blood cells coefficient, HGB, HCT was lowest in the pregnant women. The mean value of the TT4 coefficient was high in the pregnant women, while the mean value of the FT4 coefficient was low in pregnant women. The highest sensitivity was with TT4 and FT4, while the lowest seen with RBCs HGB and HCT. The specificity of HgB, RBCs and HCT was the highest, while, the lowest was in the TT4 and FT4.