The Comparison Impacts of Ginkgo Biloba and Clonazepam on Tinnitus Intensity Improvement in Individuals with Subjective Tinnitus

Abstract

Background and aim: Tinnitus is one of the most widespread ear, throat, and nose (ENT) disorders, and it has been treated with a variety of herbal and chemical medications. The comparison impacts of Ginkgo biloba (G. biloba) and Clonazepam in improving subjective tinnitus was the main purpose of this research. Material & methods: 68 patients with subjective tinnitus were selected for this work and classified into 2 identical groups. G. biloba was given to the first group (n = 34), while Clonazepam was given to the second group (n = 34), all participants are given six weeks of treatment. The parameters of adverse quality of life, tinnitus intensity, and treatment response levels were examined before and after treatment to evaluate the effect of these two mentioned drugs on changing these parameters. Results: The outcomes of this work revealed that tinnitus intensity (IT) in patients receiving clonazepam was 6.81±2.16 and 6.23±2.19 before and after treatment, respectively, but this rate for patients receiving G. biloba was 6.72±2.12 and 6.59±2.25, respectively. The results showed that both clonazepam and G. biloba had a significant impact on the variable "adverse quality of life" (P <0.05). The status of tinnitus remained unchanged at only 14.7% of patients receiving clonazepam, whereas this rate was 47.1% in patients receiving G. biloba. Conclusion: It may be stated based on the research findings that G. biloba had little effect on the recovery of tinnitus, while clonazepam was significantly more effective than G. biloba.