Synthesis, Characterization, Novel Oxazolone Derivatives of Study Cytotoxicity, Antioxidant and Antibacterial Activity in Vitro
Keywords:
oxazolones, hippuric acid, fused sodium acetate, Mono-Bis, Antioxidant & Cytotoxicity and Vitro.Abstract
By reaction aromatic aldehydes with glycine in the presence of acetic anhydride and anhydrous sodium acetate, a new family of Mono-Bis oxazolone molecules was successfully produced. The spectrum data supported the synthesis of these compounds, and the melting point, IR, 1H-NMR,13C-NMR & Mass were used to identify this Mono-Bis oxazolone chemical. Hemolysis study demonstrated that the hemolysis percentage of Mono-Bis oxazolone at (0.5 mg/ml) all concentrations were less than 4%, this result indicates the safety of their use inside the body. The antioxidant activity of the Mono-Bis oxazolone compounds against DPPH radicals was tested in vitro. The results a good.
