The Magnesium Homeostasis Role in COVID-19 Infection: A Review

Abstract

The COVID-19 pandemic starting at 2019 cause a hug panic and big challenge to scientist in a large area in the world, SARS-COV-2 is a virus with various targets and causes big health problems, the researches tend their efforts to study virus to understanding pathology and physiopathology of virus, electrolyte is one of the scientist targeting during COVID-19 era belong to its role in immune response and some vital processing functions. Magnesium homeostasis is one of the electrolyte that have role in cell functions and associated with various disease, in this review the role of magnesium level in cases with COVID-19 infection was discussed, reports found that the patients of corona virus infection have low level of Mg, especially in the patients with low oxygen and need ventilation in the Intensive Care Unit, furthermore associated Mg depletion with other disease that considered as a risk factors of COVD-19 mortality like obesity, diabetes, hypertension and cancer. It can be concluded that Mg homeostasis alteration might reasonably contribute to and aggravate long COVID syndrome, thus the flow up the Mg status is necessary and essential to support full recovery in COVID-19 patients.