A Comparative study of Hematological and biochemical parameters in leukemia patients and healthy persons

Abstract

Objective: Leukemia is classified as a type of tumor that affects the blood and bone marrow, and is considered a hematopoietic tissue tumor. The four primary forms of leukemia include acute lymphoblastic leukemia (ALL), acute myeloid leukemia (AML), chronic lymphocytic leukemia (CLL), and chronic myeloid leukemia (CML). Aim of the study: This study aimed to compare Hematological analysis and biochemical parameters (kidney, and liver functions test) of leukemia patients and healthy persons. Methods: This study was composed of 40 patients diagnosed with ALL, AML, CLL, and CML and 40 healthy people as a control group. The blood samples were collected to measure the Hematological analysis levels and kidney, liver functions test. Results: there was an increase in the level of ALK of patients with leukemia when compared to the control group and also there was no significance in the levels of urea, creatinine, and sGPT of patients with leukemia when compared with the control group, the statistical analysis showed that there was a decrease in the levels of HCT and HB and also there was no significance in the levels of WBCs, platelets, MCHC, MCH and MCV of patients with leukemia when compared with the control group. Conclusion: In leukemia patients ALK was significantly increase and significantly decrease HCT and HB when compared with healthy persons.